A study on speciation and antifungal susceptibility pattern of Candida isolates from HIV patients with oropharyngeal candidiasis and correlation with CD4 count
نویسندگان
چکیده
Background Oral candidiasis is a clinical predictor for progression to AIDS. Antifungal drug resistance is becoming a major problem with this immunedepleted population. Considering the above facts, the study was conducted to speciate and to determine the susceptibility pattern of the Candida isolates from HIV patients with oral candidiasis and to correlate it with the CD4 count of the patients.
منابع مشابه
Emergence of Azoles Resistance Candida species in Iranian AIDS defined patients with oropharyngeal candidiasis
Background and Purpose: Oropharyngeal candidiasis (OPC) and antifungal drug resistance are major health concerns in patients with human immunodeficiency virus (HIV). The increased reports of antifungal resistance and expanding drug therapy options prompted the determination of antifungal susceptibility profile. The present study was performed to determine the antifungal susceptibility of Candid...
متن کاملSpecies Identification And Antifungal Susceptibility Pattern Of Candida
s: Background &Objective: Oropharyngeal candidiasis (OPC) is a common feature associated with HIV infection. Over the past decade, reports have documented a shift away from C. albicans as a major cause of infection to non albicans Candida (NAC) species. Several NAC spp are inherently resistant to commonly used antifungal drugs. The objective of the present study was to investigate the distribut...
متن کاملحساسیت گونه‌های کاندیدای دهانی افراد آلوده به HIV نسبت به داروهای ضد قارچی تحت شرایط برون تنی در ایران
Background: Oropharyngeal candidiasis and antifungal drug resistance are major problems in HIV positive patients. The increased reports of antifungal resistance and expanding therapeutic options prompted the determination of antifungal susceptibility profile of Candida species isolates in Iranian patients living with HIV/AIDS (PLWHA) in the present study. Methods: One hundred fifty oral sampl...
متن کاملImmunosuppression Level in HIV-Positive Patients with Oropharyngeal Candidiasis
Table: Distribution of various species of Candida and antifungal resistance of various isolates in relation to CD4 count of the patients CD4 count (Cells/mm3) Isolates* (%) Candida spp. Fluconazole resistant isolates Albicans** (%) Nonalbicans*** (%) Albicans (%) Nonalbicans (%) <50 13 (21.66) 7 (15.55) 6 (40) 2 (4.44) 4 (26.66) 50–200 33 (55) 24 (53.33) 9 (60) 1 (6.66) 200–500 13 (21.66) 13 (2...
متن کاملIsolation, characterization and antifungal susceptibility pattern of Candida species causing oropharyngeal candidiasis in HIV positive patients.
A total of 100 HIV sero-positive patients with oral lesion/lesions suggestive of oropharyngeal candidiasis were studied. Candida species were isolated from 61 patients. Out of 61 isolates, 43 (70.49%) isolates were of Candida albicans and 18 (29.50%) isolates were of non albicans species. Out of 43 isolates, 2 (4.65%) isolates of Candida albicans and out of 18 isolates, 4 (22.2%) isolates of no...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2012